Description

tert-Butyl 4-(4-(Methoxycarbonyl)Phenylsulfonamido)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine and sulfonamide functional groups. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of complex, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in areas requiring sophisticated chemical scaffolds.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drug discovery programs.
• Protease Inhibitor Research: Used in the development of protease inhibitors, leveraging the sulfonamido pharmacophore for targeted biological activity.
• Kinase Inhibitor Synthesis: Serves as a core scaffold or precursor in the creation of potential kinase inhibitors for oncology and inflammatory diseases.
• Chemical Biology & Probe Development: Employed in the design and synthesis of chemical probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new synthetic routes in organic chemistry.

Basic Information

Product Name	tert-Butyl 4-(4-(Methoxycarbonyl)Phenylsulfonamido)Piperidine-1-Carboxylate
CAS No.	1286273-19-5
Molecular Formula	C18H26N2O6S
Molecular Weight	398.48 g/mol
Synonyms	1-Boc-4-[(4-methoxycarbonyl)phenylsulfonamido]piperidine; 4-[(4-Carbomethoxybenzenesulfonyl)amino]-1-piperidinecarboxylic acid tert-butyl ester; tert-Butyl 4-[[(4-methoxycarbonyl)phenyl]sulfonyl]amino]piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-[(4-methoxycarbonylphenyl)sulfonamido]piperidine; 4-(4-Methoxycarbonyl-benzenesulfonylamino)-piperidine-1-carboxylic acid tert-butyl ester; BOC-Pip(4-NHSO2-4-CO2Me-Ph)
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4-(Methoxycarbonyl)Phenylsulfonamido)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.