Description

tert-Butyl [(1-Propionylpiperidin-4-Yl)Methyl]Carbamate is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine-based molecular scaffold. This compound matters significantly for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic pathways. Pharmaceutical R&D teams and fine chemical manufacturers need it to develop new drug candidates with high specificity and efficacy. Its defined structure enables precise molecular modifications essential for modern medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel small-molecule therapeutics.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients, particularly in neurological and psychiatric drug discovery.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot and commercial production scales.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals.
• Bioconjugation & Prodrug Development: Potential use in creating prodrug forms or targeted drug delivery systems due to its carbamate and amide functionalities.

Basic Information

Product Name	tert-Butyl [(1-Propionylpiperidin-4-Yl)Methyl]Carbamate
CAS No.	1286273-04-8
Molecular Formula	C15H28N2O3
Molecular Weight	284.40 g/mol
Synonyms	Boc-4-(Aminomethyl)piperidine-1-propanamide; 1-(1-Oxopropyl)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]methyl]piperidine; 4-[(tert-Butoxycarbonylamino)methyl]-1-propionylpiperidine; tert-Butyl N-[(1-propionylpiperidin-4-yl)methyl]carbamate; 1-Propionyl-4-[(Boc-amino)methyl]piperidine; (1-Propionylpiperidin-4-yl)methylcarbamic acid tert-butyl ester; Boc-Pip(4-CH2NH2)-1-Propanamide
EINECS	Contact for details

Quality Control

Our tert-Butyl [(1-Propionylpiperidin-4-Yl)Methyl]Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP guidelines where applicable, ensuring the material meets the stringent requirements for pharmaceutical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.