Description

4-[(3-Fluoro-2-Nitrophenoxy)Methyl]Piperidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a distinct molecular structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research areas targeting central nervous system (CNS) disorders. It is essential for medicinal chemistry research, process development, and scale-up manufacturing within the pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new drug candidates, especially for neurological targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutics.
• Process Chemistry & Scale-Up: Serves as a defined starting material for the GMP-compliant synthesis of complex molecules.
• Active Pharmaceutical Ingredient (API) Synthesis: Incorporated into the synthetic pathway of potential APIs for clinical trials and commercial production.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in outsourced drug discovery and development services.
• Academic Research: Utilized in university and institutional labs for exploratory pharmacology and chemical biology studies.

Basic Information

Product Name	4-[(3-Fluoro-2-Nitrophenoxy)Methyl]Piperidine Hydrochloride
CAS No.	1286272-66-9
Molecular Formula	C12H15FN2O3 • HCl
Molecular Weight	289.72 g/mol (Free base: 254.26 g/mol)
Synonyms	4-[(3-Fluoro-2-nitrophenoxy)methyl]piperidine hydrochloride; 4-((3-Fluoro-2-nitrophenoxy)methyl)piperidine HCl; 1-(3-Fluoro-2-nitrophenoxymethyl)-4-piperidine hydrochloride; Piperidine, 4-[(3-fluoro-2-nitrophenoxy)methyl]-, hydrochloride; 1286272-66-9; UNII-9K3F3F4W6H; 9K3F3F4W6H
EINECS	Contact for details

Quality Control

Our 4-[(3-Fluoro-2-Nitrophenoxy)Methyl]Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.