Description

tert-Butyl 1-[3-Fluoro-4-(Trifluoromethyl)Benzyl]Piperidin-4-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is valued for its role as a key building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including potential candidates for central nervous system (CNS) and metabolic disorder targets.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Development: Serves as a key structural component in the research and synthesis of protease inhibitor candidates.
• Chemical Biology: Employed in the design and synthesis of chemical probes for target identification and validation.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.
• Process Chemistry: Used in route scouting and scale-up studies for the efficient production of target molecules.

Basic Information

Product Name	tert-Butyl 1-[3-Fluoro-4-(Trifluoromethyl)Benzyl]Piperidin-4-Ylcarbamate
CAS No.	1286265-98-2
Molecular Formula	C19H26F4N2O2
Molecular Weight	390.42 g/mol
Synonyms	1-[(3-Fluoro-4-(trifluoromethyl)phenyl)methyl]-4-[(2-methylpropan-2-yl)oxycarbonylamino]piperidine; 4-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-[[3-fluoro-4-(trifluoromethyl)phenyl]methyl]piperidine; tert-Butyl N-[1-[[3-fluoro-4-(trifluoromethyl)phenyl]methyl]-4-piperidyl]carbamate; 1-(3-Fluoro-4-(trifluoromethyl)benzyl)piperidin-4-yl-carbamic acid tert-butyl ester; BOC-4-amino-1-(3-fluoro-4-(trifluoromethyl)benzyl)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-[3-Fluoro-4-(Trifluoromethyl)Benzyl]Piperidin-4-Ylcarbamate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity by HPLC, identification by spectroscopic methods (IR, NMR), and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.