Description

1-(4-Fluoro-2-Methylbenzyl)Piperidin-4-Amine Dihydrochloride is a high-purity, pharmaceutically relevant intermediate characterized by its piperidine amine core functionalized with a fluorinated benzyl group. This compound matters for its role as a critical building block in modern medicinal chemistry, enabling the synthesis of targeted drug candidates. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new chemical entities, particularly for central nervous system (CNS) and other therapeutic areas where such scaffolds are explored.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Serves as a reference standard or a starting material for synthesizing probes in pharmacological and biological assays.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and methodological studies.

Basic Information

Product Name	1-(4-Fluoro-2-Methylbenzyl)Piperidin-4-Amine Dihydrochloride
CAS No.	1286265-88-0
Molecular Formula	C13H20Cl2FN3
Molecular Weight	308.22 g/mol
Synonyms	4-Amino-1-[(4-fluoro-2-methylphenyl)methyl]piperidine dihydrochloride; 1-[(4-Fluoro-2-methylphenyl)methyl]-4-piperidinamine dihydrochloride; 1-(4-Fluoro-2-methylbenzyl)piperidin-4-amine hydrochloride (1:2); 4-Amino-1-(4-fluoro-2-methylbenzyl)piperidine dihydrochloride; 1286265-88-0; UNII-6Q4V5E4K8H; 6Q4V5E4K8H
EINECS	Contact for details

Quality Control

Our 1-(4-Fluoro-2-Methylbenzyl)Piperidin-4-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.