Description

tert-Butyl n-[1-(2-Methylpropanoyl)Piperidin-4-Yl]Carbamate is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex molecules, particularly for targeting neurological and metabolic pathways. It is essential for research and production teams in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for API synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and metabolic disorder therapeutics.
• Protease Inhibitor Research: Used in the development of novel protease inhibitors due to its piperidine carbamate structure.
• Medicinal Chemistry & Drug Discovery: Serves as a versatile scaffold for constructing compound libraries and optimizing lead molecules in preclinical research.
• Peptidomimetic Synthesis: Employed in the creation of peptidomimetics, which are molecules that mimic peptides but with enhanced stability and bioavailability.
• Bioconjugation & Labeling: The reactive functional groups make it suitable for bioconjugation applications in diagnostic and therapeutic agent development.
• Contract Manufacturing (CMO/CDMO): Supplied to contract manufacturing organizations for the cGMP production of clinical trial materials and commercial APIs.

Basic Information

Product Name	tert-Butyl n-[1-(2-Methylpropanoyl)Piperidin-4-Yl]Carbamate
CAS No.	1286265-44-8
Molecular Formula	C14H26N2O3
Molecular Weight	270.37 g/mol
Synonyms	1-BOC-4-Amino-piperidine isobutyramide; tert-Butyl 4-[(2-methylpropanoyl)amino]piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(isobutyrylamino)piperidine; 4-(Isobutyrylamino)-1-piperidinecarboxylic Acid tert-Butyl Ester; N-(1-Boc-piperidin-4-yl)-2-methylpropionamide; BOC-4-Amino-piperidine Isobutyramide; 1286265-44-8; tert-Butyl N-[1-(2-methylpropanoyl)piperidin-4-yl]carbamate
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl n-[1-(2-Methylpropanoyl)Piperidin-4-Yl]Carbamate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for pharmaceutical R&D and cGMP manufacturing. A detailed Certificate of Analysis (COA) with HPLC purity, identity confirmation (IR, NMR), and impurity profile is supplied with each shipment to guarantee traceability, consistency, and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.