Description

tert-Butyl 4-((2-Amino-4-Fluorophenoxy)Methyl)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperidine scaffold with a protected amine and a fluorinated aromatic moiety. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting therapeutic areas such as central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting receptor modulation.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Employed in the multi-step synthesis of potential active pharmaceutical ingredients, especially those requiring a fluorinated phenoxy-piperidine structure.
• Chemical Biology Probes: Serves as a building block for creating molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Item	Details
Product Name	tert-Butyl 4-((2-Amino-4-Fluorophenoxy)Methyl)Piperidine-1-Carboxylate
CAS No.	1286264-60-5
Molecular Formula	C17H25FN2O3
Molecular Weight	324.39 g/mol
Synonyms	1-Boc-4-[(2-Amino-4-fluorophenoxy)methyl]piperidine; 4-[(2-Amino-4-fluorophenoxy)methyl]piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-[(2-amino-4-fluorophenoxy)methyl]piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-[(2-amino-4-fluorophenoxy)methyl]piperidine; BOC-4-((2-Amino-4-fluorophenoxy)methyl)piperidine; 1286264-60-5; 4-(2-Amino-4-fluorophenoxymethyl)piperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-((2-Amino-4-Fluorophenoxy)Methyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.