Description

tert-Butyl 4-[3-(Methoxycarbonyl)Benzylamino]Piperidine-1-Carboxylate is a high-purity, protected piperidine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and development, enabling the construction of complex molecules with potential therapeutic activity. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Scaffold: Used for structure-activity relationship (SAR) studies and lead optimization due to its versatile piperidine core and protected amine functionality.
• Peptidomimetic Synthesis: Serves as a constrained amino acid analog in the design of peptide-like molecules with enhanced metabolic stability.
• Chemical Biology Probe Development: Employed in the synthesis of tool compounds for studying biological pathways and target validation.
• Custom Synthesis Building Block: Provides a protected amine handle for multi-step synthesis, allowing for selective deprotection and further functionalization.
• Library Synthesis for High-Throughput Screening: A valuable component for generating diverse compound libraries to identify new hits in drug discovery campaigns.

Basic Information

Product Name	tert-Butyl 4-[3-(Methoxycarbonyl)Benzylamino]Piperidine-1-Carboxylate
CAS No.	1286264-55-8
Molecular Formula	C19H28N2O4
Molecular Weight	348.44 g/mol
Synonyms	1-Boc-4-[(3-methoxycarbonylbenzyl)amino]piperidine; 1-(tert-Butoxycarbonyl)-4-[[(3-methoxycarbonylphenyl)methyl]amino]piperidine; tert-Butyl 4-[[(3-methoxycarbonylphenyl)methyl]amino]-1-piperidinecarboxylate; 4-[(3-Methoxycarbonyl-benzylamino)-piperidine-1-carboxylic acid tert-butyl ester; 1-Boc-4-(3-methoxycarbonylbenzylamino)piperidine; BOC-4-(3-Methoxycarbonylbenzylamino)piperidine; 1286264-55-8
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-[3-(Methoxycarbonyl)Benzylamino]Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.