Description

tert-Butyl 1-(2-Bromobenzyl)Piperidin-4-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate featuring a bromobenzyl-substituted piperidine core protected by a Boc (tert-butoxycarbonyl) group. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing complex molecules with targeted biological activity. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and oncology drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of potential drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize the biological profile of new chemical entities.
• API (Active Pharmaceutical Ingredient) Development: Serves as a crucial fragment in the construction of more complex active molecules during process development and scale-up.
• Chemical Biology Probes: Can be utilized to develop tool compounds for investigating biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific, high-purity intermediates.

Basic Information

Product Name	tert-Butyl 1-(2-Bromobenzyl)Piperidin-4-Ylcarbamate
CAS No.	1286263-42-0
Molecular Formula	C17H25BrN2O2
Molecular Weight	369.30 g/mol
Synonyms	1-(2-Bromobenzyl)piperidine-4-carboxylic acid tert-butylamide; Boc-4-amino-1-(2-bromobenzyl)piperidine; tert-Butyl N-[1-[(2-bromophenyl)methyl]-4-piperidyl]carbamate; 1-(2-Bromobenzyl)-4-(Boc-amino)piperidine; 4-[(tert-Butoxycarbonyl)amino]-1-(2-bromobenzyl)piperidine; 1-(2-Bromobenzyl)piperidin-4-yl-carbamic acid tert-butyl ester; BOC-Piperidine-4-yl-(2-bromobenzyl)amine
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-(2-Bromobenzyl)Piperidin-4-Ylcarbamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP (current Good Manufacturing Practice) guidelines where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.