Description

3-Amino-6-[4-[[2-(Dimethylamino)-1-Methylethyl]Sulfonyl]Phenyl]-n-Phenyl-2-Pyrazinecarboxamide is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel, targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of innovative small-molecule drugs, particularly in oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of investigational new drugs (INDs) and new chemical entities (NCEs).
• Oncology Drug Research: Used in the development of targeted kinase inhibitors and other anti-cancer compounds due to its specific molecular scaffold.
• Medicinal Chemistry & R&D: Employed in structure-activity relationship (SAR) studies and lead optimization processes within drug discovery pipelines.
• Biochemical Research: Acts as a tool compound or a reference standard in biochemical assays to study specific biological pathways and protein interactions.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	3-Amino-6-[4-[[2-(Dimethylamino)-1-Methylethyl]Sulfonyl]Phenyl]-n-Phenyl-2-Pyrazinecarboxamide
CAS No.	1286238-55-8
Molecular Formula	C24H28N6O3S
Molecular Weight	480.58 g/mol
Synonyms	3-Amino-6-[4-[[2-(dimethylamino)-1-methylethyl]sulfonyl]phenyl]-N-phenylpyrazine-2-carboxamide; 3-Amino-N-phenyl-6-[4-[(2-(dimethylamino)propan-2-yl)sulfonyl]phenyl]pyrazine-2-carboxamide; UNII-1K1W9F2Q5F; 1K1W9F2Q5F; 3-Amino-6-(4-{[2-(dimethylamino)-1-methylethyl]sulfonyl}phenyl)-N-phenyl-2-pyrazinecarboxamide; 3-Amino-6-[4-[[2-(dimethylamino)-1-methylethyl]sulfonyl]phenyl]-N-phenylpyrazine-2-carboxamide
EINECS	Contact for details

Quality Control

Our 3-Amino-6-[4-[[2-(Dimethylamino)-1-Methylethyl]Sulfonyl]Phenyl]-n-Phenyl-2-Pyrazinecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.