Description

(S)-tert-Butyl 3-(Ethylsulfonamido)Piperidine-1-Carboxylate is a high-purity chiral piperidine derivative, serving as a critical building block in modern pharmaceutical synthesis. Its value lies in providing a stereochemically defined scaffold for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system and metabolic diseases. This advanced intermediate is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and biotechnology industries who require reliable, high-quality raw materials for complex synthetic routes.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, especially in medicinal chemistry programs.
• API Development: Used as a building block in the research and scale-up production of Active Pharmaceutical Ingredients (APIs).
• Protease Inhibitor Synthesis: A potential precursor in the synthesis of inhibitors targeting specific enzymatic pathways.
• Asymmetric Synthesis: Employed in stereoselective reactions to introduce the (S)-configured piperidine moiety into complex molecular architectures.
• Chemical Biology Research: Useful as a tool compound or a labeled precursor in biochemical and pharmacological studies.
• Process Chemistry & Optimization: Serves as a standard or starting material for developing and optimizing robust, scalable manufacturing processes.

Basic Information

Product Name	(S)-tert-Butyl 3-(Ethylsulfonamido)Piperidine-1-Carboxylate
CAS No.	1286209-13-9
Molecular Formula	C12H24N2O4S
Molecular Weight	292.40 g/mol
Synonyms	1-Boc-3-[(ethylsulfonyl)amino]-(S)-piperidine; (S)-1-(tert-Butoxycarbonyl)-3-(ethylsulfonylamino)piperidine; tert-Butyl (3S)-3-(ethylsulfonylamino)piperidine-1-carboxylate; (S)-N-Boc-3-amino-3-(ethylsulfonamido)piperidine; 1-Boc-3-(ethylsulfonamido)-(S)-piperidine; (S)-3-(Ethylsulfonamido)-1-Boc-piperidine; (S)-1-Boc-3-(ethylsulfonylamino)piperidine; BOC-(S)-3-(Ethylsulfonylamino)piperidine
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 3-(Ethylsulfonamido)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity, NMR, and LC-MS for structural confirmation and impurity profiling. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and specific impurity limits to ensure compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.