Description

(S)-4-Fluoro-n-(Piperidin-3-Yl)Benzamidehydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial interest. This compound is valued for its role in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and oncology drug discovery pipelines. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• CNS Drug Development: Serves as a precursor for compounds targeting neurological receptors and enzymes.
• Oncology Research: Employed in the development of kinase inhibitors and other targeted cancer therapies.
• Peptidomimetics & Bioactive Molecule Synthesis: The piperidine scaffold is integral to creating molecules that mimic peptide structures.
• Custom Synthesis & Scale-Up: Supplied for process development and cGMP manufacturing of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(S)-4-Fluoro-n-(Piperidin-3-Yl)Benzamidehydrochloride
CAS No.	1286208-24-9
Molecular Formula	C12H16ClFN2O
Molecular Weight	258.72 g/mol
Synonyms	(S)-4-Fluoro-N-(piperidin-3-yl)benzamide hydrochloride; (3S)-4-Fluoro-N-(3-piperidyl)benzamide hydrochloride; (S)-3-[(4-Fluorobenzoyl)amino]piperidine hydrochloride; 4-Fluoro-N-[(3S)-piperidin-3-yl]benzamide hydrochloride; Benzamide, 4-fluoro-N-[(3S)-3-piperidinyl]-, hydrochloride (1:1); (S)-N-(Piperidin-3-yl)-4-fluorobenzamide HCl
EINECS	Contact for details

Quality Control

Our (S)-4-Fluoro-n-(Piperidin-3-Yl)Benzamidehydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical R&D and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.