Description

(R)-n-(Propan-2-Yl)Piperidin-3-Amine Dihydrochloride is a high-purity chiral amine salt, widely recognized as a critical pharmaceutical intermediate and building block in advanced organic synthesis. Its value lies in providing a stereochemically defined piperidine scaffold essential for developing active pharmaceutical ingredients (APIs) with specific biological activity. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Ligand Synthesis: Used in the preparation of chiral ligands for asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides with improved efficacy and selectivity.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological targets and pathways.
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes for commercial API manufacturing.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and medicinal chemistry programs.

Basic Information

Product Name	(R)-n-(Propan-2-Yl)Piperidin-3-Amine Dihydrochloride
CAS No.	1286207-72-4
Molecular Formula	C8H20Cl2N2
Molecular Weight	215.16 g/mol
Synonyms	(R)-N-Isopropyl-3-aminopiperidine dihydrochloride; (R)-3-Amino-N-isopropylpiperidine dihydrochloride; (R)-1-(Propan-2-yl)piperidin-3-amine dihydrochloride; (R)-N-(1-Methylethyl)-3-piperidinamine dihydrochloride; (3R)-N-(Propan-2-yl)piperidin-3-amine dihydrochloride; (R)-3-Isopropylaminopiperidine dihydrochloride; (R)-IPAP dihydrochloride
EINECS	Contact for details

Quality Control

Our (R)-n-(Propan-2-Yl)Piperidin-3-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.