Description

(R)-2-(Dimethylamino)-n-(Piperidin-3-Yl)Acetamide Hydrochloride is a high-purity chiral intermediate and building block of significant interest in advanced pharmaceutical research and development. Its value lies in its specific stereochemistry and functional groups, which are critical for creating targeted bioactive molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries working on novel therapeutic agents, particularly in central nervous system (CNS) and receptor-targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs), especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery projects targeting specific receptors.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for candidate drugs under Good Manufacturing Practice (GMP) conditions.
• Ligand and Probe Synthesis: Utilized in the creation of specialized chemical probes for biological target identification and validation in biochemical assays.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective synthesis to introduce specific three-dimensional configurations into complex molecules.

Basic Information

Product Name	(R)-2-(Dimethylamino)-n-(Piperidin-3-Yl)Acetamide Hydrochloride
CAS No.	1286207-71-3
Molecular Formula	C9H20N3O·HCl
Molecular Weight	219.74 g/mol (Free base: 183.28 g/mol)
Synonyms	(R)-N-(3-Piperidinyl)-2-(dimethylamino)acetamide hydrochloride; (R)-2-(Dimethylamino)-N-(piperidin-3-yl)acetamide HCl; (R)-DMAPA Hydrochloride; (3R)-N-[2-(Dimethylamino)acetyl]piperidin-3-amine hydrochloride; (R)-3-[[2-(Dimethylamino)acetyl]amino]piperidine hydrochloride; UNII-9J5F8L8B2F; 1286207-71-3; (R)-enantiomer of DMAPA-HCl
EINECS	Contact for details

Quality Control

Our (R)-2-(Dimethylamino)-n-(Piperidin-3-Yl)Acetamide Hydrochloride is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We support development with custom synthesis and scale-up services under quality agreements, adhering to ICH guidelines for impurity identification and control.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.