Description

(S)-tert-Butyl 1-(Cyclobutylmethyl)Pyrrolidin-3-Ylcarbamate is a high-purity chiral intermediate of significant importance in advanced pharmaceutical synthesis. This compound is valued for its role as a key building block in the development of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, where precise stereochemistry and reliable quality are paramount.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs).
• Neurological Drug Research: Used in the development of compounds targeting neurological disorders and CNS pathways.
• Asymmetric Synthesis: Serves as a precursor for ligands or catalysts in stereoselective chemical transformations.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization processes.
• Process Chemistry Development: Used for scaling up synthetic routes from laboratory to pilot and commercial production.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control.

Basic Information

Product Name	(S)-tert-Butyl 1-(Cyclobutylmethyl)Pyrrolidin-3-Ylcarbamate
CAS No.	1286207-43-9
Molecular Formula	C15H28N2O2
Molecular Weight	268.40 g/mol
Synonyms	(S)-1-(Cyclobutylmethyl)-3-((tert-butoxycarbonyl)amino)pyrrolidine; (S)-tert-Butyl (1-(cyclobutylmethyl)pyrrolidin-3-yl)carbamate; (S)-N-Boc-1-(Cyclobutylmethyl)-3-aminopyrrolidine; (S)-3-((tert-Butoxycarbonyl)amino)-1-(cyclobutylmethyl)pyrrolidine; tert-Butyl (3S)-1-(cyclobutylmethyl)-3-pyrrolidinylcarbamate; (S)-1-(Cyclobutylmethyl)pyrrolidin-3-yl-carbamic acid tert-butyl ester; BOC-(S)-1-(Cyclobutylmethyl)-3-aminopyrrolidine
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 1-(Cyclobutylmethyl)Pyrrolidin-3-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with stringent specifications for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.