Description

(R)-tert-Butyl 3-(2-Methoxyacetamido)Piperidine-1-Carboxylate is a high-purity, chiral piperidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules, enabling precise control over the final product's biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential drug candidates, especially for central nervous system (CNS) and metabolic disease targets.
• Agrochemical Research: Used in the development of novel, stereoselective pesticides and herbicides where specific chirality is required for efficacy.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric hydrogenation and other catalytic processes.
• Peptidomimetics & Bioactive Molecule Construction: The protected piperidine core is integral for designing and synthesizing peptide analogs and other bioactive compounds.
• Chemical Biology Probe Development: Utilized to create tool compounds for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring high chiral purity.

Basic Information

Product Name	(R)-tert-Butyl 3-(2-Methoxyacetamido)Piperidine-1-Carboxylate
CAS No.	1286207-06-4
Molecular Formula	C13H24N2O4
Molecular Weight	272.34 g/mol
Synonyms	1-Boc-3-[(2-methoxyacetyl)amino]-(3R)-piperidine; (R)-1-Boc-3-(2-Methoxyacetamido)piperidine; tert-Butyl (3R)-3-[(2-methoxyacetyl)amino]piperidine-1-carboxylate; (R)-N-Boc-3-amino-2-methoxyacetamide piperidine; (3R)-1-(tert-Butoxycarbonyl)-3-[(2-methoxyacetyl)amino]piperidine; (R)-3-(Methoxyacetylamino)piperidine-1-carboxylic acid tert-butyl ester; BOC-(R)-3-(2-Methoxyacetamido)piperidine
EINECS	Contact for details

Quality Control

Our (R)-tert-Butyl 3-(2-Methoxyacetamido)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral excess, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.