Description

1-(4-Methoxyphenyl)-2-Piperazinone Hydrochloride is a high-purity pharmaceutical intermediate and research chemical. This compound is valued for its role as a key building block in the synthesis of complex organic molecules, particularly in medicinal chemistry. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Organic Synthesis Building Block: Serves as a versatile synthon for constructing complex heterocyclic compounds and piperazine derivatives.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Biochemical Research: Utilized in proteomics and enzyme inhibition studies due to its specific structural features.

Basic Information

Product Name	1-(4-Methoxyphenyl)-2-Piperazinone Hydrochloride
CAS No.	1284247-69-3
Molecular Formula	C11H15ClN2O2
Molecular Weight	242.70 g/mol
Synonyms	1-(4-Methoxyphenyl)piperazin-2-one hydrochloride; 4-Methoxyphenyl-2-piperazinone HCl; 2-Piperazinone, 1-(4-methoxyphenyl)-, hydrochloride; 1-(p-Methoxyphenyl)-2-piperazinone hydrochloride; 1-(4-Methoxyphenyl)-2-oxopiperazine hydrochloride; 1-(4-Methoxyphenyl)piperazine-2-one hydrochloride; 1284247-69-3
EINECS	Contact for details

Quality Control

Our 1-(4-Methoxyphenyl)-2-Piperazinone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.