Description

tert-Butyl (3-Bromo-5-Methylpyridin-2-Yl)Carbamate is a high-purity, protected pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for drug discovery and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting neurological disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the construction of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Academic and R&D: Utilized in university and institutional laboratories for methodological development and novel heterocyclic chemistry research.

Basic Information

Product Name	tert-Butyl (3-Bromo-5-Methylpyridin-2-Yl)Carbamate
CAS No.	1284210-79-2
Molecular Formula	C11H15BrN2O2
Molecular Weight	287.15 g/mol
Synonyms	Boc-3-Bromo-5-methyl-2-aminopyridine; 2-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-bromo-5-methylpyridine; tert-Butyl N-(3-bromo-5-methyl-2-pyridinyl)carbamate; 3-Bromo-5-methylpyridin-2-amine, N-Boc protected; 2-Amino-3-bromo-5-methylpyridine, N-Boc derivative; Boc-3-Br-5-Me-2-APy; (3-Bromo-5-methyl-pyridin-2-yl)-carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (3-Bromo-5-Methylpyridin-2-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area %)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.