Description

3-Cyclopropylamino-Piperidine-1-Carboxylic Acid Benzyl Ester CAS NO 1284112-64-6 is a high-value, nitrogen-containing heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key chiral intermediate, offering a versatile piperidine scaffold functionalized with both cyclopropylamino and benzyl ester groups for precise molecular construction. It is primarily needed by research and development chemists in the pharmaceutical industry for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in areas targeting central nervous system (CNS) disorders and other therapeutic applications.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the research and synthesis of novel drug candidates, especially in neurological and psychiatric therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its modifiable piperidine core.
• API Synthesis: Serves as a key precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Employed in the development of molecular probes to study biological pathways and enzyme functions.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material in stereoselective synthesis to create enantiomerically pure compounds.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for pharmaceutical clients.

Basic Information

Product Name	3-Cyclopropylamino-Piperidine-1-Carboxylic Acid Benzyl Ester
CAS No.	1284112-64-6
Molecular Formula	C16H22N2O2
Molecular Weight	274.36 g/mol
Synonyms	Benzyl 3-(cyclopropylamino)piperidine-1-carboxylate; 1-Piperidinecarboxylic acid, 3-(cyclopropylamino)-, phenylmethyl ester; 3-(Cyclopropylamino)-1-piperidinecarboxylic acid benzyl ester; 3-Cyclopropylaminopiperidine-1-carboxylic acid benzyl ester; 3-Cyclopropylamino-1-piperidinecarboxylic acid benzyl ester; 1-Carbobenzyloxy-3-cyclopropylaminopiperidine; Cbz-3-Cyclopropylaminopiperidine
EINECS	Contact for details

Quality Control

Our 3-Cyclopropylamino-Piperidine-1-Carboxylic Acid Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.