Description

tert-Butyl 5-Bromopyridin-3-Yl(Propyl)Carbamate is a high-purity, advanced pharmaceutical intermediate characterized by its bromopyridine and carbamate functional groups. This compound is of significant commercial value for its role as a critical building block in modern medicinal chemistry, enabling the synthesis of complex, bioactive molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in kinase inhibitor programs.
• Agrochemical Synthesis: Used as a precursor in the development of advanced crop protection agents and herbicides.
• Ligand & Catalyst Development: Serves as a versatile scaffold for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and polymers.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production under cGMP conditions.
• Academic & Industrial R&D: Utilized in exploratory chemistry for constructing complex heterocyclic systems with potential biological activity.

Basic Information

Product Name	tert-Butyl 5-Bromopyridin-3-Yl(Propyl)Carbamate
CAS No.	1280786-95-9
Molecular Formula	C13H19BrN2O2
Molecular Weight	315.21 g/mol
Synonyms	tert-Butyl N-(5-bromopyridin-3-yl)-N-propylcarbamate; Carbamic acid, N-(5-bromo-3-pyridinyl)-N-propyl-, 1,1-dimethylethyl ester; 5-Bromo-N-propylpyridin-3-amine, N-Boc protected; 3-((tert-Butoxycarbonyl)(propyl)amino)-5-bromopyridine; tert-Butyl (5-bromo-3-pyridyl)(propyl)carbamate; Boc-5-Bromo-3-(propylamino)pyridine; 1280786-95-9
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-Bromopyridin-3-Yl(Propyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with ICH guidelines, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.