Description

3-Bromo-2-(n-T-Butylamino)-5-Trifluoromethylpyridine is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine, a tertiary-butylamino group, and a trifluoromethyl substituent, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals with unique electronic or optical properties.
• Chemical Synthesis: Acts as a versatile scaffold for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex pyridine motifs into target molecules.
• Life Science Reagents: Utilized in the design and synthesis of molecular probes, diagnostic agents, and biochemical tools for research purposes.

Basic Information

Product Name	3-Bromo-2-(n-T-Butylamino)-5-Trifluoromethylpyridine
CAS No.	1280786-64-2
Molecular Formula	C10H12BrF3N2
Molecular Weight	297.12 g/mol
Synonyms	3-Bromo-2-(tert-butylamino)-5-(trifluoromethyl)pyridine; 2-(tert-Butylamino)-3-bromo-5-trifluoromethylpyridine; 3-Bromo-2-[(1,1-dimethylethyl)amino]-5-(trifluoromethyl)pyridine; 3-Bromo-2-(tert-butylamino)-5-(trifluoromethyl)pyridine; tert-Butyl-[3-bromo-5-(trifluoromethyl)pyridin-2-yl]amine
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-(n-T-Butylamino)-5-Trifluoromethylpyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.