Description

T-Butyl 6-Chloro-2-Pyridinecarboxylate is a high-purity pyridine derivative building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where precise molecular architecture is paramount. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require specific pyridine-based structures.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	T-Butyl 6-Chloro-2-Pyridinecarboxylate
CAS No.	1280786-59-5
Molecular Formula	C10H12ClNO2
Molecular Weight	213.66 g/mol
Synonyms	tert-Butyl 6-chloropicolinate; 6-Chloro-2-pyridinecarboxylic acid tert-butyl ester; 2-Pyridinecarboxylic acid, 6-chloro-, 1,1-dimethylethyl ester; 6-Chloropicolinic acid tert-butyl ester; tert-Butyl 6-chloro-2-pyridinecarboxylate; 6-Chloro-2-(tert-butoxycarbonyl)pyridine; t-Butyl 6-chloropicolinate
EINECS	Contact for details

Quality Control

Our T-Butyl 6-Chloro-2-Pyridinecarboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP standards where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.