Description

2-Bromo-5-Methyl-4,5,6,7-Tetrahydrothiazolo[4,5-C]Pyridine is a high-value, heterocyclic organic building block featuring a fused thiazole and piperidine ring system. This compound is critical for pharmaceutical research and development, serving as a versatile synthetic intermediate for the creation of novel active pharmaceutical ingredients (APIs). It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to incorporate complex, functionalized heterocycles into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its modifiable bromo and methyl substituents.
• Agrochemical Development: Serves as a building block for novel herbicides, fungicides, and insecticides that require specific heterocyclic scaffolds for bioactivity.
• Chemical Biology Probes: Employed in the development of tool compounds and molecular probes for studying biological pathways and target validation.
• Material Science: Potential intermediate for synthesizing specialty chemicals, ligands for catalysis, or components in advanced organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to outsourcing partners who require reliable, high-purity building blocks for custom synthesis projects.

Basic Information

Product Name	2-Bromo-5-Methyl-4,5,6,7-Tetrahydrothiazolo[4,5-C]Pyridine
CAS No.	1280704-26-8
Molecular Formula	C7H9BrN2S
Molecular Weight	233.13 g/mol
Synonyms	2-Bromo-5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[4,5-c]pyridine; 4,5,6,7-Tetrahydro-2-bromo-5-methylthiazolo[4,5-c]pyridine; Thiazolo[4,5-c]pyridine, 2-bromo-4,5,6,7-tetrahydro-5-methyl-; 1280704-26-8; 2-Bromo-5-methyl-4,5,6,7-tetrahydrothiazolo[4,5-c]pyridine; 5-Methyl-2-bromo-4,5,6,7-tetrahydrothiazolo[4,5-c]pyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Methyl-4,5,6,7-Tetrahydrothiazolo[4,5-C]Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent quality for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.