Description

5-{[(2-Methyl-2-Propanyl)Oxy]Carbonyl}-4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrazine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, particularly within therapeutic areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used as a versatile scaffold in hit-to-lead optimization and structure-activity relationship (SAR) studies.
• API Synthesis: Incorporated into the final synthetic route for complex active pharmaceutical ingredients requiring a tetrahydropyrazolopyrazine core.
• Bioconjugation & Probe Development: The carboxylic acid functional group allows for conjugation to other molecules, useful in creating biochemical probes or targeted drug delivery systems.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	5-{[(2-Methyl-2-Propanyl)Oxy]Carbonyl}-4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrazine-3-Carboxylic Acid
CAS No.	1280214-48-3
Molecular Formula	C13H17N3O4
Molecular Weight	279.29 g/mol
Synonyms	5-[(tert-Butoxycarbonyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-3-carboxylic acid; 5-(Boc)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-3-carboxylic acid; tert-Butyl 3-carboxy-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-5-carboxylate; 5-Boc-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-3-carboxylic acid; Pyrazolo[1,5-a]pyrazine-3-carboxylic acid, 4,5,6,7-tetrahydro-5-[[(2-methyl-2-propanyl)oxy]carbonyl]-; CAS 1280214-48-3
EINECS	Contact for details

Quality Control

Our 5-{[(2-Methyl-2-Propanyl)Oxy]Carbonyl}-4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrazine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research and pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.