Description

tert-Butyl 2,5-Bis(((Methylsulfonyl)Oxy)Methyl)Pyrrolidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its bis-mesylate functional groups. This compound is of critical importance for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in sophisticated organic synthesis and process development.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• API Synthesis: Serves as a versatile building block for constructing complex molecular architectures found in target active pharmaceutical ingredients.
• Proteolysis-Targeting Chimera (PROTAC) Development: Used in the construction of linker components for bifunctional molecules in targeted protein degradation research.
• Agrochemical Research: Employed as an intermediate in the development of new pesticides and herbicides with specific activity profiles.
• Chemical Biology Probes: Facilitates the creation of tool compounds and molecular probes for studying biological pathways and target engagement.
• Process Chemistry & Scale-Up: Provides a reliable and well-defined starting material for optimizing synthetic routes from laboratory to pilot and commercial scale.

Basic Information

Item	Details
Product Name	tert-Butyl 2,5-Bis(((Methylsulfonyl)Oxy)Methyl)Pyrrolidine-1-Carboxylate
CAS No.	1279821-96-3
Molecular Formula	C13H25NO8S2
Molecular Weight	411.47 g/mol
Synonyms	1-Boc-2,5-bis(mesyloxymethyl)pyrrolidine; 1-(tert-Butoxycarbonyl)-2,5-bis((methylsulfonyloxy)methyl)pyrrolidine; tert-Butyl 2,5-bis(methanesulfonyloxymethyl)pyrrolidine-1-carboxylate; 2,5-Bis(mesyloxymethyl)-1-N-Boc-pyrrolidine; Pyrrolidine-1-carboxylic acid, 2,5-bis(((methylsulfonyl)oxy)methyl)-, 1,1-dimethylethyl ester; 1279821-96-3; 1-Boc-2,5-bis(OMS)pyrrolidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 2,5-Bis(((Methylsulfonyl)Oxy)Methyl)Pyrrolidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.