Description

Benzyl 3-(Trifluoromethyl)Piperazine-1-Carboxylate is a high-value, fluorinated piperazine derivative serving as a critical building block in advanced organic synthesis. Its core value lies in the trifluoromethyl group, which is strategically positioned to modulate the physicochemical and metabolic properties of target molecules, enhancing their potency and bioavailability. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients. The CAS number for this compound is 1279815-93-8.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in constructing advanced fungicides, herbicides, and insecticides where the trifluoromethyl group imparts improved biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of novel fluorinated polymers and advanced materials with unique surface properties.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring the introduction of a functionalized piperazine scaffold.
• Chemical Biology Probes: Useful for creating tagged molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	Benzyl 3-(Trifluoromethyl)Piperazine-1-Carboxylate
CAS No.	1279815-93-8
Molecular Formula	C13H15F3N2O2
Molecular Weight	288.26 g/mol
Synonyms	1-CBz-3-(Trifluoromethyl)piperazine; Benzyl 3-(Trifluoromethyl)-1-piperazinecarboxylate; 3-(Trifluoromethyl)piperazine-1-carboxylic acid benzyl ester; 1-Piperazinecarboxylic acid, 3-(trifluoromethyl)-, phenylmethyl ester; 1-N-CBz-3-Trifluoromethylpiperazine; 3-Trifluoromethyl-1-CBz-piperazine; 1-Benzyloxycarbonyl-3-trifluoromethylpiperazine
EINECS	Contact for details

Quality Control

Our Benzyl 3-(Trifluoromethyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment supports compliance with cGMP guidelines for advanced intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.