Description

Methyl 5-(Aminomethyl)Pyrazine-2-Carboxylate Hydrochloride is a high-purity, pharmaceutically relevant building block, specifically designed for the synthesis of complex active pharmaceutical ingredients (APIs). Its core value lies in providing a critical, functionalized pyrazine scaffold essential for modern drug discovery and development programs. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in creating novel therapeutics, particularly in areas like kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Kinase Inhibitor Synthesis: Serves as a crucial building block for the development of novel kinase inhibitors used in oncology and other therapeutic areas.
• Medicinal Chemistry Research: Enables the exploration of new chemical entities (NCEs) and structure-activity relationships (SAR) in drug discovery.
• Peptidomimetic & Heterocyclic Chemistry: Used to incorporate functionalized pyrazine motifs into more complex peptidomimetic and heterocyclic compounds.
• Chemical Biology Probes: Facilitates the creation of specialized probes for studying biological processes and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	Methyl 5-(Aminomethyl)Pyrazine-2-Carboxylate Hydrochloride
CAS No.	1279698-22-4
Molecular Formula	C7H10ClN3O2
Molecular Weight	203.63 g/mol
Synonyms	5-(Aminomethyl)pyrazine-2-carboxylic acid methyl ester hydrochloride; Methyl 5-(aminomethyl)pyrazine-2-carboxylate HCl; 2-Pyrazinecarboxylic acid, 5-(aminomethyl)-, methyl ester, hydrochloride; Methyl 5-aminomethylpyrazine-2-carboxylate hydrochloride; 1279698-22-4; Methyl 5-(aminomethyl)-2-pyrazinecarboxylate hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl 5-(Aminomethyl)Pyrazine-2-Carboxylate Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support development and commercial projects with material suitable for research use and can supply grades aligned with current Good Manufacturing Practice (cGMP) standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual unknown impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.