Description

5-Chloro-6-Methylpyridine-2-Sulfonyl Chloride is a high-value, multi-functional chemical intermediate characterized by its reactive sulfonyl chloride and halogenated pyridine moieties. This compound is essential for the synthesis of complex molecules, enabling the introduction of the sulfonamide group, a key pharmacophore in modern drug discovery. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its bioactivity-enhancing properties.
• Material Science Research: Serves as a precursor for creating functionalized polymers and advanced materials with specific surface properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: A key reagent for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	5-Chloro-6-Methylpyridine-2-Sulfonyl Chloride
CAS No.	1279213-03-4
Molecular Formula	C7H5Cl2NO2S
Molecular Weight	246.09 g/mol
Synonyms	2-Pyridinesulfonyl chloride, 5-chloro-6-methyl-; 5-Chloro-6-methyl-2-pyridinesulfonyl chloride; 5-Chloro-6-methylpyridine-2-sulfonyl chloride; 2-Chlorosulfonyl-5-chloro-6-methylpyridine; 6-Methyl-5-chloropyridine-2-sulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-6-Methylpyridine-2-Sulfonyl Chloride is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is available for each lot, confirming identity, purity, and impurity profiles via validated methods such as HPLC, NMR, and GC.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.