Description

5-Bromo-4-Methyl-2-(Methylsulfonyl)Pyridine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a bromine substituent for cross-coupling reactions and a methylsulfonyl group as a versatile activating and leaving group. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries who require sophisticated intermediates for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its reactive sites for structural diversification.
• Material Science Research: Serves as a building block for creating functionalized ligands, organic semiconductors, and other specialty chemicals.
• Cross-Coupling Reactions: The bromine atom is an excellent handle for Suzuki, Stille, and Buchwald-Hartwig amination reactions to form complex biaryl and heteroaryl systems.
• Sulfonyl Chemistry: The methylsulfonyl group can act as a strong electron-withdrawing group, a directing group in metalation, or be displaced in nucleophilic substitution reactions.

Basic Information

Product Name	5-Bromo-4-Methyl-2-(Methylsulfonyl)Pyridine
CAS No.	1279106-02-3
Molecular Formula	C8H8BrNO2S
Molecular Weight	266.12 g/mol
Synonyms	2-Bromo-3-Methyl-6-(Methylsulfonyl)Pyridine; 5-Bromo-4-methyl-2-methylsulfonylpyridine; 2-(Methylsulfonyl)-5-bromo-4-methylpyridine; 5-Bromo-4-methylpyridine-2-sulfonyl methyl; 1279106-02-3; 5-Bromo-4-methyl-2-methanesulfonylpyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Methyl-2-(Methylsulfonyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.