Description

1-(2-Chloro-Pyridin-4-Yl)-Piperazine Dihydrochloride is a high-purity, versatile chemical building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry research for central nervous system (CNS) and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Serves as a building block for creating molecular probes to study biological pathways and protein interactions.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Academic Research: A valuable reagent for universities and research institutes exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	1-(2-Chloro-Pyridin-4-Yl)-Piperazine Dihydrochloride
CAS No.	1279029-86-5
Molecular Formula	C9H13ClN3·2HCl
Molecular Weight	287.59 g/mol
Synonyms	1-(2-Chloropyridin-4-yl)piperazine dihydrochloride; 4-(2-Chloropyridin-4-yl)piperazine dihydrochloride; 2-Chloro-4-(piperazin-1-yl)pyridine dihydrochloride; 1-(2-Chloro-4-pyridinyl)piperazine dihydrochloride; Piperazine, 1-(2-chloro-4-pyridinyl)-, dihydrochloride; CAS 1279029-86-5
EINECS	Contact for details

Quality Control

Our 1-(2-Chloro-Pyridin-4-Yl)-Piperazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.