Description

2-A]Pyrazine-6-Carbonitrile is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its functionalized pyrazine ring, which serves as a critical precursor for constructing complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly for kinase inhibitors and other biologically active heterocycles.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides that require functionalized pyrazine cores.
• Material Science Research: Serves as a precursor for the creation of organic electronic materials, ligands for catalysis, and specialty polymers.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, tags, and activity-based probes for studying biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	2-A]Pyrazine-6-Carbonitrile
CAS No.	1276056-81-5
Molecular Formula	C6H3N3
Molecular Weight	117.11 g/mol
Synonyms	6-Cyanopyrazine-2-carbonitrile; 2,6-Dicyanopyrazine; Pyrazine-2,6-dicarbonitrile; 2,6-Pyrazinedicarbonitrile; 1,4-Diazine-2,6-dicarbonitrile; 2,6-Dicyano-1,4-diazine; 2,6-Bis(cyan)pyrazine
EINECS	Contact for details

Quality Control

Our 2-A]Pyrazine-6-Carbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.