Description

(S)-tert-Butyl 3-(2-Hydroxyethyl)Piperazine-1-Carboxylate is a high-purity chiral piperazine derivative, serving as a critical building block in modern pharmaceutical synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with defined stereochemistry, essential for developing active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries, particularly those focused on creating novel therapeutics and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of potential drug candidates, including kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• API Development: Used in constructing the core piperazine scaffold found in numerous marketed pharmaceuticals, enabling precise control over the 3D structure of the final molecule.
• Agrochemical Research: Serves as a precursor in the development of advanced pesticides and herbicides where specific chirality impacts biological activity.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and contract research organizations (CROs/CMOs) specializing in chiral chemistry.
• Chemical Biology & Proteomics: Can be utilized in the design and synthesis of molecular probes and linkers for studying biological systems.
• Academic & Industrial R&D: Fundamental building block in medicinal chemistry laboratories for exploring new chemical entities and structure-activity relationships (SAR).

Basic Information

Product Name	(S)-tert-Butyl 3-(2-Hydroxyethyl)Piperazine-1-Carboxylate
CAS No.	1273577-11-9
Molecular Formula	C11H22N2O3
Molecular Weight	230.31 g/mol
Synonyms	1-Boc-3-(2-hydroxyethyl)piperazine, (S)-enantiomer; (S)-1-(tert-Butoxycarbonyl)-3-(2-hydroxyethyl)piperazine; tert-Butyl (S)-3-(2-hydroxyethyl)piperazine-1-carboxylate; (S)-3-(2-Hydroxyethyl)-1-Boc-piperazine; (S)-1-Boc-3-(2-Hydroxyethyl)piperazine; (S)-N-Boc-3-(2-Hydroxyethyl)piperazine; (S)-3-(2-Hydroxyethyl)piperazine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 3-(2-Hydroxyethyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC to ensure enantiomeric purity and identity confirmation via spectroscopic methods. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions or an inert atmosphere to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.