Description

tert-Butyl 7,8-Dihydro-6H-Spiro[[1,2,4]Triazolo[1,5-A]Pyrazine-5,4-Piperidine]-1-Carboxylate (Wx105713) is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and fused heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) and other therapeutic agents. The CAS number for this compound is 1273566-99-6.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates, particularly those targeting neurological pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new molecules with improved efficacy and safety profiles.
• API Development: Employed in the pilot-scale and commercial-scale production of Active Pharmaceutical Ingredients (APIs) requiring its specific spirocyclic scaffold.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the global pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl 7,8-Dihydro-6H-Spiro[[1,2,4]Triazolo[1,5-A]Pyrazine-5,4-Piperidine]-1-Carboxylate (Wx105713)
CAS No.	1273566-99-6
Molecular Formula	C14H21N5O2
Molecular Weight	291.35 g/mol
Synonyms	tert-Butyl 7,8-dihydro-6H-spiro[[1,2,4]triazolo[1,5-a]pyrazine-5,4'-piperidine]-1'-carboxylate; WX-105713; WX105713; 1'-Boc-6'H-spiro[piperidine-4,5'-[1,2,4]triazolo[1,5-a]pyrazine]; 1,1-Dimethylethyl 7,8-dihydro-6H-spiro[[1,2,4]triazolo[1,5-a]pyrazine-5,4'-piperidine]-1'-carboxylate; BOC-protected spiro-triazolopyrazine-piperidine.
EINECS	Contact for details

Quality Control

Our tert-Butyl 7,8-Dihydro-6H-Spiro[[1,2,4]Triazolo[1,5-A]Pyrazine-5,4-Piperidine]-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.