Description

1-Benzyl-5-(Aminomethyl)Piperidin-2-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperidinone scaffold with benzyl and aminomethyl functional groups. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially those targeting neurological receptors.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex heterocyclic molecules through reactions involving its amine and ketone functionalities.
• Preclinical & Clinical Research: Serves as a starting material or intermediate in the synthesis of compounds for pharmacological screening and early-stage clinical trials.
• Process Chemistry Development: Employed in route scouting and optimization for scalable API manufacturing processes.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical labs.

Basic Information

Product Name	1-Benzyl-5-(Aminomethyl)Piperidin-2-One
CAS No.	1272756-11-2
Molecular Formula	C13H18N2O
Molecular Weight	218.30 g/mol
Synonyms	5-(Aminomethyl)-1-benzylpiperidin-2-one; 1-Benzyl-5-(aminomethyl)-2-piperidinone; 2-Piperidinone, 5-(aminomethyl)-1-benzyl-; 1272756-11-2; 1-Benzyl-5-(aminomethyl)piperidin-2-one; 5-(Aminomethyl)-1-benzyl-2-piperidone; 1-Benzyl-5-(aminomethyl)-2-piperidone
EINECS	Contact for details

Quality Control

Our 1-Benzyl-5-(Aminomethyl)Piperidin-2-One is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis by GC, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.