Description

(R)-tert-Butyl 3-(2-Hydroxyethyl)Piperazine-1-Carboxylate is a high-purity chiral piperazine derivative, serving as a critical building block in modern organic synthesis. Its primary value lies in its role as a versatile intermediate for constructing complex molecules with defined stereochemistry, which is essential for developing active pharmaceutical ingredients (APIs). This compound is particularly sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel therapeutic agents and specialty chemicals. The CAS number for this compound is 1272421-10-9.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) agents and receptor modulators.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where specific chirality impacts biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Employed in the design and synthesis of peptidomimetic compounds for medicinal chemistry applications.
• Custom Chemical Synthesis: A valuable starting material for contract research organizations (CROs) and CDMOs producing custom, high-value fine chemicals.

Basic Information

Product Name	(R)-tert-Butyl 3-(2-Hydroxyethyl)Piperazine-1-Carboxylate
CAS No.	1272421-10-9
Molecular Formula	C11H22N2O3
Molecular Weight	230.31 g/mol
Synonyms	1-Boc-3-(2-hydroxyethyl)-(R)-piperazine; (R)-1-(tert-Butoxycarbonyl)-3-(2-hydroxyethyl)piperazine; tert-Butyl (R)-3-(2-hydroxyethyl)piperazine-1-carboxylate; (R)-3-(2-Hydroxyethyl)-1-(tert-butoxycarbonyl)piperazine; (R)-1-N-Boc-3-(2-hydroxyethyl)piperazine; (R)-N-Boc-3-(2-hydroxyethyl)piperazine; (3R)-1-(tert-Butoxycarbonyl)-3-(2-hydroxyethyl)piperazine; BOC-(R)-3-(2-Hydroxyethyl)piperazine
EINECS	Contact for details

Quality Control

Our (R)-tert-Butyl 3-(2-Hydroxyethyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.