Description

1-(5-Bromopyridin-3-Yl)Cyclopropanecarbonitrile is a high-purity, advanced pharmaceutical intermediate featuring a unique bromopyridine-cyclopropane hybrid structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of potential drug candidates and active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Serves as a building block for developing novel pesticides and herbicides due to its heterocyclic core.
• Ligand and Catalyst Development: The bromopyridine moiety can be utilized to create novel ligands for catalysis and metal-organic frameworks.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Item	Details
Product Name	1-(5-Bromopyridin-3-Yl)Cyclopropanecarbonitrile
CAS No.	1272357-22-8
Molecular Formula	C9H7BrN2
Molecular Weight	223.07 g/mol
Synonyms	1-(5-Bromo-3-pyridinyl)cyclopropanecarbonitrile; 3-(1-Cyanocyclopropyl)-5-bromopyridine; 5-Bromo-3-(1-cyanocyclopropyl)pyridine; Cyclopropanecarbonitrile, 1-(5-bromo-3-pyridinyl)-; 1-(5-Bromopyridin-3-yl)cyclopropane-1-carbonitrile
EINECS	Contact for details

Quality Control

Our 1-(5-Bromopyridin-3-Yl)Cyclopropanecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.