Description

3,6-Dibromopyrazine-2-Carbaldehyde is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic positioning of reactive bromine atoms and an aldehyde group on the pyrazine scaffold, enabling precise and diverse molecular construction. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly for kinase inhibitors and other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a versatile starting material for creating specialized chelating ligands and organocatalysts.
• Material Science Building Block: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Cross-Coupling Reactions: The bromine substituents make it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions.
• Chemical Research & Development: A valuable tool for medicinal and synthetic chemists exploring new chemical space and reaction pathways.

Basic Information

Item	Detail
Product Name	3,6-Dibromopyrazine-2-Carbaldehyde
CAS No.	1270497-54-5
Molecular Formula	C5H2Br2N2O
Molecular Weight	265.89 g/mol
Synonyms	2,5-Dibromopyrazine-6-carboxaldehyde; 3,6-Dibromo-2-pyrazinecarboxaldehyde; 2-Pyrazinecarboxaldehyde, 3,6-dibromo-; 3,6-Dibromopyrazinecarbaldehyde; Dibromopyrazine carboxaldehyde
EINECS	Contact for details

Quality Control

Our 3,6-Dibromopyrazine-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.