Description

1,2-Piperazinedicarboxylic Acid, 1-(1,1-Dimethylethyl) 2-Methyl Ester, Hydrochloride (1:1) is a high-purity, protected piperazine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in the pharmaceutical sector. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals requiring a functionalized piperazine core.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS), as anthelmintics, or as protease inhibitors.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides where the piperazine moiety contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetic Research: Employed in the design and construction of peptidomimetics and other bioactive compounds that mimic peptide structures.
• Chemical Biology Probes: Utilized to develop molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	1,2-Piperazinedicarboxylic Acid, 1-(1,1-Dimethylethyl) 2-Methyl Ester, Hydrochloride (1:1)
CAS No.	1269449-40-2
Molecular Formula	C11H21N2O4 • HCl
Molecular Weight	280.76 g/mol
Synonyms	tert-Butyl 4-(methoxycarbonyl)piperazine-1-carboxylate hydrochloride; 1-Boc-4-(methoxycarbonyl)piperazine hydrochloride; 1-(tert-Butoxycarbonyl)-4-(methoxycarbonyl)piperazine hydrochloride; 1-tert-Butyl 2-methyl piperazine-1,2-dicarboxylate hydrochloride; 4-(Methoxycarbonyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester hydrochloride; N-Boc-4-(carbonmethoxy)piperazine HCl; Piperazine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Every batch of our 1,2-Piperazinedicarboxylic Acid, 1-(1,1-Dimethylethyl) 2-Methyl Ester, Hydrochloride (1:1) is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, is performed to verify identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.