Description

(4-Aminopiperidin-1-Yl)(Cyclopentyl)Methanone Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a defined piperidine-based scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for synthesizing novel drug candidates. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers targeting therapeutic areas such as central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for CNS-targeting drugs.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Protease Inhibitor Development: Serves as a core structural motif in the design of protease inhibitors due to its piperidine moiety.
• Library Synthesis for High-Throughput Screening (HTS): Employed to create diverse compound libraries for biological screening against novel targets.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP guidelines.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and pharmacology.

Basic Information

Product Name	(4-Aminopiperidin-1-Yl)(Cyclopentyl)Methanone Hydrochloride
CAS No.	1269397-20-7
Molecular Formula	C11H21ClN2O
Molecular Weight	232.75 g/mol
Synonyms	Cyclopentyl(4-aminopiperidin-1-yl)methanone hydrochloride; 1-(Cyclopentanecarbonyl)-4-aminopiperidine hydrochloride; N-Cyclopentyl-4-aminopiperidine-1-carboxamide hydrochloride; 4-Amino-1-(cyclopentylcarbonyl)piperidine hydrochloride; 4-Aminopiperidine-1-carboxylic acid cyclopentylamide hydrochloride
EINECS	Contact for details

Quality Control

Our (4-Aminopiperidin-1-Yl)(Cyclopentyl)Methanone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting development work under ISO and cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.