Description

Methyl 4-(Piperazin-1-Yl)Benzoate Hydrochloride is a high-purity pharmaceutical intermediate and building block of significant synthetic utility. This compound matters for its role as a key precursor in the development of active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring piperazine-based scaffolds. Pharmaceutical R&D teams and fine chemical manufacturers need it for synthesizing potential drug candidates, where its defined structure and purity are critical for successful downstream reactions and regulatory filings.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• API Synthesis: Used in the production route of Active Pharmaceutical Ingredients (APIs) that incorporate a substituted benzoate and piperazine moiety.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.

Basic Information

Product Name	Methyl 4-(Piperazin-1-Yl)Benzoate Hydrochloride
CAS No.	1269393-85-2
Molecular Formula	C12H17ClN2O2
Molecular Weight	256.73 g/mol
Synonyms	Methyl 4-(1-Piperazinyl)benzoate hydrochloride; 4-(Piperazin-1-yl)benzoic acid methyl ester hydrochloride; Methyl p-(piperazin-1-yl)benzoate HCl; Benzoic acid, 4-(1-piperazinyl)-, methyl ester, hydrochloride; Methyl 4-piperazin-1-ylbenzoate hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl 4-(Piperazin-1-Yl)Benzoate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.