Description

5-Fluoro-1-(Pyridin-2-Yl)-1H-Pyrazole-4-Carbonitrile is a high-value heterocyclic building block featuring a pyrazole core substituted with a fluorine atom and a nitrile group. This compound is critical for medicinal chemistry research and pharmaceutical development, serving as a versatile intermediate for constructing novel active molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of targeted drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the design and production of advanced herbicides, fungicides, and insecticides, leveraging its fluorinated pyrazole structure.
• Material Science Research: Serves as a precursor for the development of specialty chemicals, ligands for catalysis, and functional materials.
• Chemical Biology Probes: Employed in the creation of molecular probes and tags for studying biological processes and target engagement.

Basic Information

Product Name	5-Fluoro-1-(Pyridin-2-Yl)-1H-Pyrazole-4-Carbonitrile
CAS No.	1269293-12-0
Molecular Formula	C9H5FN4
Molecular Weight	188.16 g/mol
Synonyms	5-Fluoro-1-(2-pyridinyl)-1H-pyrazole-4-carbonitrile; 1-(Pyridin-2-yl)-5-fluoro-1H-pyrazole-4-carbonitrile; 5-Fluoro-1-pyridin-2-yl-1H-pyrazole-4-carbonitrile; 1269293-12-0; 5-Fluoro-1-(2-pyridyl)-1H-pyrazole-4-carbonitrile
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1-(Pyridin-2-Yl)-1H-Pyrazole-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.