Description

Ethyl 6-Bromo-3-Hydroxy-5-Methylpyrazine-2-Carboxylate is a high-purity, functionalized pyrazine derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex heterocyclic scaffolds, enabling the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to build sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that leverage the pyrazine core for bioactivity.
• Material Science Precursor: Serves as a starting material for creating functionalized organic molecules used in electronic materials or ligands for catalysis.
• Academic & Contract Research: Essential for medicinal chemistry programs and synthetic methodology research in university and CRO (Contract Research Organization) laboratories.
• Custom Synthesis: Employed by fine chemical manufacturers for the bespoke production of complex molecules for client-specific projects.

Basic Information

Product Name	Ethyl 6-Bromo-3-Hydroxy-5-Methylpyrazine-2-Carboxylate
CAS No.	1269026-22-3
Molecular Formula	C8H9BrN2O3
Molecular Weight	261.07 g/mol
Synonyms	6-Bromo-3-hydroxy-5-methylpyrazine-2-carboxylic acid ethyl ester; Ethyl 6-bromo-3-hydroxy-5-methyl-2-pyrazinecarboxylate; 2-Pyrazinecarboxylic acid, 6-bromo-3-hydroxy-5-methyl-, ethyl ester; 6-Bromo-5-methyl-3-oxo-3,4-dihydropyrazine-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 6-Bromo-3-Hydroxy-5-Methylpyrazine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.