Description

(2S,6S)-2,6-Dimethyl-4-Oxo-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, stereochemically defined piperidine derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in providing a rigid, functionalized scaffold for constructing complex molecules with precise three-dimensional control. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing new active ingredients, particularly for applications requiring specific stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where the specific spatial orientation of the molecule is crucial for bioactivity.
• Catalyst and Ligand Development: Serves as a precursor for designing novel chiral catalysts and ligands used in asymmetric synthesis to induce enantioselectivity.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying enzyme mechanisms and biological pathways due to its defined stereochemistry and functional groups.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) working on client-specific, complex molecular targets.

Basic Information

Product Name	(2S,6S)-2,6-Dimethyl-4-Oxo-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1268816-80-3
Molecular Formula	C12H21NO3
Molecular Weight	227.30 g/mol
Synonyms	tert-Butyl (2S,6S)-2,6-dimethyl-4-oxopiperidine-1-carboxylate; 1-Boc-2,6-dimethyl-4-piperidone (stereoisomer); (2S,6S)-1-(tert-Butoxycarbonyl)-2,6-dimethyl-4-piperidone; 4-Piperidinone, 2,6-dimethyl-1-[(1,1-dimethylethoxy)carbonyl]-, (2S,6S)-; BOC-2,6-Dimethyl-4-piperidone (S,S-isomer); (S,S)-1-Boc-2,6-dimethylpiperidin-4-one
EINECS	Contact for details

Quality Control

Our (2S,6S)-2,6-Dimethyl-4-Oxo-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. We provide material with typical purity grades suitable for research and commercial scale-up, supported by comprehensive analytical documentation. Certificates of Analysis (COA) detailing identity, purity (by HPLC), chiral purity, and impurity profiles are available for every batch to ensure compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Chiral Purity (Chiral HPLC)	≥99.0% de
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.