Description

(2S,3R)-2-Methyl-5-Oxo-4-(Phenylmethyl)-3-Morpholinecarboxylic Acid CAS NO 1268474-69-6 is a high-purity chiral morpholine derivative, a critical advanced pharmaceutical intermediate (API) and building block in modern organic synthesis. Its value lies in its stereochemically defined structure, which is essential for imparting specific biological activity in final drug molecules. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel therapeutic agents, particularly in areas requiring complex chiral scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of active pharmaceutical ingredients (APIs) for central nervous system (CNS) drugs, antivirals, and other specialty therapeutics.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry Development: Used in the scale-up and optimization of synthetic routes for complex molecules in pilot plants and commercial manufacturing.
• Fine Chemical Synthesis: An intermediate for producing specialty chemicals, agrochemicals, and other high-value, complex organic molecules.

Basic Information

Product Name	(2S,3R)-2-Methyl-5-Oxo-4-(Phenylmethyl)-3-Morpholinecarboxylic Acid
CAS No.	1268474-69-6
Molecular Formula	C14H17NO4
Molecular Weight	263.29 g/mol
Synonyms	(2S,3R)-2-Methyl-5-oxo-4-benzylmorpholine-3-carboxylic acid; 4-Benzyl-2-methyl-5-oxomorpholine-3-carboxylic acid, (2S,3R)-; (3R,2S)-2-Methyl-5-oxo-4-(phenylmethyl)-3-morpholinecarboxylic acid; (2S,3R)-4-Benzyl-2-methyl-5-oxomorpholine-3-carboxylic acid; (S,R)-2-Methyl-5-oxo-4-benzylmorpholine-3-carboxylic acid; Chiral morpholine-3-carboxylic acid derivative; Benzyl morpholone carboxylic acid; 1268474-69-6
EINECS	Contact for details

Quality Control

Our (2S,3R)-2-Methyl-5-Oxo-4-(Phenylmethyl)-3-Morpholinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with pharmaceutical intermediate standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.