Description

1-Cyclopropanecarbonyl-3,3-Dimethylpiperazine is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperazine-based structure with a cyclopropanecarbonyl substituent. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key synthon in the research and commercial synthesis of novel drug candidates, especially for central nervous system (CNS) and anti-infective agents.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Manufacturing: Used in the multi-step synthesis of complex APIs, where its specific stereochemistry and functional groups are essential.
• Contract Research & Development (CRO/CDMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Bioconjugation & Probe Development: Potential utility in creating chemical probes or conjugates for biochemical and diagnostic applications due to its reactive carbonyl group.

Basic Information

Product Name	1-Cyclopropanecarbonyl-3,3-Dimethylpiperazine
CAS No.	1268008-16-7
Molecular Formula	C10H18N2O
Molecular Weight	182.26 g/mol
Synonyms	3,3-Dimethylpiperazine-1-carboxylic acid cyclopropylamide; Cyclopropanecarboxylic acid (3,3-dimethylpiperazin-1-yl)amide; 1-(Cyclopropanecarbonyl)-3,3-dimethylpiperazine; N-Cyclopropyl-3,3-dimethylpiperazine-1-carboxamide; 3,3-Dimethyl-1-(cyclopropylcarbonyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-Cyclopropanecarbonyl-3,3-Dimethylpiperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.