Description

1-((2S,5S)-2,5-Dimethylpiperazin-1-yl)ethanone is a high-purity chiral piperazine derivative of significant importance in advanced organic synthesis. This compound serves as a critical building block for the development of novel pharmaceutical intermediates and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate its specific stereochemistry into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of potential drug candidates, particularly in medicinal chemistry programs.
• API Development: Used as a precursor or a core structural motif in the development of new Active Pharmaceutical Ingredients requiring a specific (2S,5S) stereochemical configuration.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and asymmetric synthesis.
• Agrochemical Research: Serves as a building block for novel crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis for clients.

Basic Information

Product Name	1-((2S,5S)-2,5-Dimethylpiperazin-1-yl)ethanone
CAS No.	1267873-19-7
Molecular Formula	C8H16N2O
Molecular Weight	156.23 g/mol
Synonyms	1-Acetyl-(2S,5S)-2,5-dimethylpiperazine; (2S,5S)-1-Acetyl-2,5-dimethylpiperazine; N-Acetyl-(2S,5S)-2,5-dimethylpiperazine; 1-[(2S,5S)-2,5-Dimethyl-1-piperazinyl]ethanone; Ethanone, 1-[(2S,5S)-2,5-dimethyl-1-piperazinyl]-; (2S,5S)-2,5-Dimethyl-1-(1-oxoethyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-((2S,5S)-2,5-Dimethylpiperazin-1-yl)ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and scale-up. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.