Description

tert-Butyl 4-(2-Hydroxy-2-Methylpropyl)Piperazine-1-Carboxylate is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecules with precise stereochemistry and pharmacological properties. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the piperazine moiety for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital component for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke fine chemicals for client projects.
• Polymer Modification: Can be utilized to introduce functional amine groups into polymer backbones for specialty materials.

Basic Information

Product Name	tert-Butyl 4-(2-Hydroxy-2-Methylpropyl)Piperazine-1-Carboxylate
CAS No.	1267341-14-9
Molecular Formula	C13H26N2O3
Molecular Weight	258.36 g/mol
Synonyms	1-Boc-4-(2-hydroxy-2-methylpropyl)piperazine; 1-(tert-Butoxycarbonyl)-4-(2-hydroxy-2-methylpropyl)piperazine; tert-Butyl 4-(2-hydroxy-2-methylpropyl)-1-piperazinecarboxylate; 4-(2-Hydroxy-2-methylpropyl)-1-piperazinecarboxylic acid tert-butyl ester; 1-Boc-4-(2-hydroxyisobutyl)piperazine; N-Boc-4-(2-hydroxy-2-methylpropyl)piperazine; BOC-Piperazine-OH-iBu; 1267341-14-9
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-Hydroxy-2-Methylpropyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.