Description

4-(Aminomethyl)-3,5-Dibromopyridine is a halogenated pyridine derivative featuring both bromine substituents and an aminomethyl functional group, making it a versatile and valuable bifunctional building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research where precise halogenation and amine functionality are critical. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing active pharmaceutical ingredients (APIs), ligands, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, where the bromine atoms and amine group allow for further derivatization.
• Ligand and Catalyst Development: Acts as a building block for creating complex chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Material Science Research: Employed in the synthesis of specialty polymers and functional organic materials requiring specific halogenated motifs.
• Cross-Coupling Reactions: The bromine substituents make it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).

Basic Information

Item	Details
Product Name	4-(Aminomethyl)-3,5-Dibromopyridine
CAS No.	1265895-10-0
Molecular Formula	C7H8Br2N2
Molecular Weight	279.96 g/mol
Synonyms	3,5-Dibromo-4-(aminomethyl)pyridine; 4-(Aminomethyl)-3,5-dibromopyridine; (3,5-Dibromopyridin-4-yl)methanamine; 3,5-Dibromo-4-pyridinemethanamine; 4-Pyridinemethanamine, 3,5-dibromo-; 1265895-10-0
EINECS	Contact for details

Quality Control

Our 4-(Aminomethyl)-3,5-Dibromopyridine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing specifications such as purity (by HPLC), identity (by IR and NMR), and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.