Description

tert-Butyl (4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Yl)Methylcarbamate is a high-purity, protected boronic ester derivative designed for advanced organic synthesis. This compound is a critical building block in pharmaceutical research and development, enabling the formation of complex molecular architectures through cross-coupling reactions. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Research: Used to create novel active ingredients for crop protection and pest control agents.
• Material Science: Serves as a monomer or functionalization agent in the development of advanced polymers and organic electronic materials.
• Chemical Biology: Employed in the synthesis of probes and ligands for target identification and validation studies.
• Process Chemistry: Utilized in route scouting and optimization for the scalable production of fine chemicals.
• Academic Research: A valuable reagent for methodology development and exploring new catalytic transformations in organic chemistry.

Basic Information

Item	Details
Product Name	tert-Butyl (4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Yl)Methylcarbamate
CAS No.	1264282-48-5
Molecular Formula	C17H27BN2O4
Molecular Weight	334.22 g/mol
Synonyms	tert-Butyl N-[[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-pyridyl]methyl]carbamate; 3-[[(tert-Butoxycarbonyl)amino]methyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Boc-Protected 3-(Aminomethyl)-4-boronopyridine Pinacol Ester; 4-(Boc-aminomethyl)-3-pyridylboronic acid pinacol ester; (4-(Boc-aminomethyl)pyridin-3-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Yl)Methylcarbamate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications and test results. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere when appropriate to maintain stability and purity. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.