Description

4-(Hydroxymethyl)Pyridine-2-Boronic Acid Pinacol Ester is a high-value, multifunctional boronic ester building block essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for constructing pyridine-containing drug candidates, including kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific pyridine-heterocycle architectures for enhanced bioactivity.
• Material Science & OLED Development: Serves as a building block for creating electron-transport materials, host materials, and emissive layer components in organic light-emitting diodes (OLEDs) and other electronic devices.
• Ligand & Catalyst Design: Employed in the synthesis of novel bidentate and tridentate ligands for transition metal catalysis, enabling more efficient and selective chemical transformations.
• Chemical Biology & Probe Development: Utilized to create molecular probes and bioconjugates for studying biological processes and enzyme functions.
• Polymer & Resin Modification: Incorporated into polymer backbones or as pendant groups to impart specific chemical functionality or reactivity to advanced polymeric materials.

Basic Information

Item	Detail
Product Name	4-(Hydroxymethyl)Pyridine-2-Boronic Acid Pinacol Ester
CAS No.	1264162-23-3
Molecular Formula	C13H20BNO3
Molecular Weight	249.12 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(hydroxymethyl)pyridine; 4-(Hydroxymethyl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-(Hydroxymethyl)pyridine-2-boronic acid pinacol ester; 4-Pyridinemethanol, 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; (4-(Hydroxymethyl)pyridin-2-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-(Hydroxymethyl)Pyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with customer specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.